5-Methoxy-2-pyridinamine(CAS: 10167-97-2)

5-Methoxy-2-pyridinamine is a solid with a crystalline form. Its molecular weight is approximately 141.15 g/mol. It has limited water solubility, being slightly soluble in water. Chemically, it is mildly basic and can react with acidic compounds. It is stable under normal conditions but may degrade under acidic or basic conditions.

5-Methoxy-2-pyridinamine can be synthesized by the reaction of 2-pyridinemethanamine with methanol in the presence of an acid catalyst. The process involves nucleophilic substitution, leading to the formation of the methoxy group. The yield is typically around 85%, and the reaction is selective and efficient.

5-Methoxy-2-pyridinamine is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of sensors and as an intermediate in the synthesis of other pyridine derivatives for various applications, including polymers and semiconductors.

Handling 5-Methoxy-2-pyridinamine requires the use of personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a closed, cool, and dry place. Spills should be contained and treated according to the Material Safety Data Sheet (MSDS). It is important to work in a well-ventilated area or a fume hood to minimize exposure to this compound.