2-Phenyl-3-pyridinamine

Basic Information

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CAS Number

101601-80-3

Molecular Formula

C11H10N2

Molecular Weight

170.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

338.5°Cat760mmHg

Density

1.133

Flash Point

185.1°C

Refractive Index

1.625

SMILES

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C1=CC=C(C=C1)C2=C(C=CC=N2)N

InChI

InChI=1S/C11H10N2/c12-10-7-4-8-13-11(10)9-5-2-1-3-6-9/h1-8H,12H2

InChIKey

XTHJCITVHCRQRD-UHFFFAOYSA-N

LogP

2.3308

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

152

Safety Information

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Hazard Statement

Synonyms & References

English

XTHJCITVHCRQRD-UHFFFAOYSA-N
2-phenyl-3-pyridinylamine
MFCD04114113
2-PHENYL-PYRIDIN-3-YLAMINE
CS-0156482
AKOS006343952
InChI=1/C11H10N2/c12-10-7-4-8-13-11(10)9-5-2-1-3-6-9/h1-8H,12H2
XTHJCITVHCRQRD-UHFFFAOYA
SY064850
AM86053
A800413
N10445
DTXSID90376448
PS-4930
AB17894
2-phenyl-3-aminopyridine
SCHEMBL3027615
101601-80-3
J-511557
3-Amino-2-phenylpyridine
aminophenylpyridine
EN300-149621
2-phenylpyridin-3-amine
2-Phenylpyridine-3-ylamine
3-Pyridinamine, 2-phenyl-
FT-0659913
2-phenyl-3-pyridinamine
2-Phenylpyridin-3-amine
2-PHENYL-3-PYRIDINAMINE
2-Phenylpyridin-3-amine, (3-Aminopyridin-2-yl)benzene

MDL Number

MFCD04114113

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Phenyl-3-pyridinamine (CAS: 101601-80-3)?

2-Phenyl-3-pyridinamine is a crystalline compound with a molecular weight of approximately 168.18 g/mol. It is slightly soluble in water and has a high solubility in organic solvents like ethanol and acetone. The compound is moderately reactive towards nucleophiles and can undergo substitution reactions. It exhibits a melting point around 160-162°C.

How is 2-Phenyl-3-pyridinamine (CAS: 101601-80-3) typically synthesized?

2-Phenyl-3-pyridinamine is commonly synthesized via the condensation of 3-aminopyridine with phenyl isocyanate. The reaction typically proceeds with good yield (up to 85%) and selectivity, although the use of a catalyst like 4-dimethylaminopyridine (DMAP) can enhance the reaction efficiency.

What industries use 2-Phenyl-3-pyridinamine (CAS: 101601-80-3)?

2-Phenyl-3-pyridinamine finds applications in the pharmaceutical industry as a starting material for drug synthesis. It is also used in the polymer industry for the development of functionalized polymers. Additionally, it has potential uses in the production of sensors and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 2-Phenyl-3-pyridinamine (CAS: 101601-80-3)?

When handling 2-Phenyl-3-pyridinamine, it is crucial to ensure proper ventilation and use a fume hood. Wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place, away from oxidizers and flammable materials. In case of a spill, use appropriate absorbent materials and follow safety data sheet (SDS) guidelines for disposal.