1-(2-Bromophenyl)piperazine

Basic Information

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CAS Number

1011-13-8

Molecular Formula

C10H13BrN2

Molecular Weight

241.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

94-96℃/0.02mm

Density

1.386

Flash Point

157.6°C

Refractive Index

1.575

SMILES

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C1CN(CCN1)C2=CC=CC=C2Br

InChI

InChI=1S/C10H13BrN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2

InChIKey

JVTRURBMYILQDA-UHFFFAOYSA-N

LogP

1.8586999999999996

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

157

Safety Information

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Hazard Statement

Synonyms & References

English

Piperazine, 1-(2-bromophenyl)-
1-(2-bromophenyl)piperazine
JVTRURBMYILQDA-UHFFFAOYSA-N
Z594274798
AMY32954
1-(o-bromophenyl)piperazine
FS-1607
MFCD03844726
J-502961
1011-13-8
AKOS009157493
1-(2-Bromophenyl)-piperazine
FT-0633240
EN300-77081
SCHEMBL232830
A800331
SY023464
DTXSID60373747
1-(2-Bromophenyl)piperazine
AC1MBV7J
ACMC-2097ub
CTK3J9552
Piperazine,1-(2-bromophenyl)-
PubChem9275
SureCN232830
Vortioxetine impurity B
Vortioxetine Impurity 13
1- (2- bromine phenyl) piperazine
1-(2-BROMOPHENYL)-PIPERAZINE >97%

MDL Number

MFCD03844726

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 1-(2-Bromophenyl)piperazine (CAS: 1011-13-8)?

1-(2-Bromophenyl)piperazine (CAS: 1011-13-8) is a crystalline solid with a molecular weight of approximately 242.05 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive with oxidizing agents and can undergo substitution reactions. It does not react with common reagents such as acids or bases under normal conditions.

How is 1-(2-Bromophenyl)piperazine (CAS: 1011-13-8) typically synthesized?

1-(2-Bromophenyl)piperazine is typically synthesized through a multistep process involving bromination of piperazine, followed by coupling with 2-bromophenol. This process requires precise control of reaction conditions, including temperature and the use of appropriate catalysts to achieve high yields and selectivity. Common solvents used include dichloromethane or acetonitrile.

What industries use 1-(2-Bromophenyl)piperazine (CAS: 1011-13-8)?

1-(2-Bromophenyl)piperazine (CAS: 1011-13-8) is primarily used in the pharmaceutical industry for the development of new drug compounds. It also has applications in the polymer industry for the production of specialized polymers and in the sensor industry for creating chemical sensors. Additionally, it may be used in the semiconductor industry for manufacturing processes.

What precautions should be taken when handling 1-(2-Bromophenyl)piperazine (CAS: 1011-13-8)?

When handling 1-(2-Bromophenyl)piperazine (CAS: 1011-13-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or under a fume hood to prevent inhalation. Spills should be handled immediately by wiping up with absorbent material and disposing of according to safety protocols. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal procedures.