5-Nitro-2-pyridinecarbonitrile

Basic Information

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CAS Number

100367-55-3

Molecular Formula

C6H3N3O2

Molecular Weight

149.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

344.5°C at 760 mmHg

Density

1.41

Flash Point

162.2℃

Refractive Index

1.583

SMILES

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C1=CC(=NC=C1[N+](=O)[O-])C#N

InChI

InChI=1S/C6H3N3O2/c7-3-5-1-2-6(4-8-5)9(10)11/h1-2,4H

InChIKey

YZDHDHMJKCKESU-UHFFFAOYSA-N

LogP

1.38468

Complexity

202

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

EN300-82649
2-PYRIDINECARBONITRILE, 5-NITRO-
PB15869
5-nitro-2-pyridinecarbonitrile
MFCD07368184
AMY33600
SCHEMBL4016419
5-nitropyridine-2-carbonitrile
J-517883
CS-W003373
100367-55-3
2-Cyano-5-nitropyridine
A800111
FT-0647746
5-Nitropicolinonitrile
5-Nitro-picolinonitrile
DTXSID80437411
YZDHDHMJKCKESU-UHFFFAOYSA-N
AC-6784
METHYL6-[(AMINOCARBONOTHIOYL)AMINO]HEXANOATE
AKOS006285810
SY013181
DS-0629
6-CYANO-3-NITROPYRIDINE
2-Pyridinecarbonitrile,5-nitro-(9CI)

MDL Number

MFCD07368184

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3)?

5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3) falls under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a category 4 skin corrosion/irritation agent. It is also subject to the European Union's Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) legislation, which requires manufacturers and importers to register substances with the European Chemicals Agency (ECHA). Additionally, the U.S. Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) have specific requirements for the handling and disposal of this compound.

Are there alternatives to 5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3) in synthesis?

Alternatives to 5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3) in synthesis include other pyridine derivatives such as 2-pyridinecarbonitrile, 3-nitro-2-pyridinecarbonitrile, and 4-nitro-2-pyridinecarbonitrile. Additionally, using other nitrating agents like concentrated nitric acid or mixed nitrating agents can provide similar functionalities with different reaction profiles.

What is the market or research trend for 5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3)?

The market for 5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3) is primarily driven by its use in pharmaceuticals and agrochemicals, where it serves as a key intermediate. Research trends indicate a focus on developing more efficient synthesis routes and exploring its potential in more specialized applications, such as in catalysis and material science. Emerging trends also include the study of its environmental impact and the development of safer alternatives.

How should waste containing 5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3) be handled?

Waste containing 5-Nitro-2-pyridinecarbonitrile (CAS: 100367-55-3) should be handled according to local and international regulations. It is advisable to collect and store waste in appropriate containers with tight seals to prevent leakage. For proper disposal, incineration is often recommended due to its stability and potential for complete destruction. Alternatively, professional waste disposal services that adhere to environmental protection standards can be utilized. Always ensure that the waste is neutralized if necessary and that all precautions to prevent environmental contamination are taken.