Compound Q&A

How is [(2R,6R)-4-Benzyl-6-methyl-2-morpholinyl]methanol (CAS: 1821773-67-4) typically synthesized?

Answer

[(2R,6R)-4-Benzyl-6-methyl-2-morpholinyl]methanol
[(2R,6R)-4-Benzyl-6-methyl-2-morpholinyl]methanol (CAS: 1821773-67-4) can be synthesized through a multi-step process involving the preparation of 2-benzyl-6-methylmorpholine, followed by reaction with benzyl alcohol. This involves a Sonogashira coupling and a Grignard reaction. The final product is obtained with good yield and selectivity, making it a useful intermediate in organic synthesis.

About

English Name [(2R,6R)-4-Benzyl-6-methyl-2-morpholinyl]methanol
Molecular Formula C13H19NO2
Molecular Weight 221.3 g/mol
SMILES C[C@@H]1CN(C[C@@H](O1)CO)Cc2ccccc2
InChIKey VGPHTTKTZQGSHW-DGCLKSJQSA-N
Last Updated: 2026-03-10 14:55

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