Compound Q&A

How is 2-Fluoro-pyridine-3-sulfonyl chloride (CAS: 1089330-70-0) typically synthesized?

Answer

2-Fluoro-pyridine-3-sulfonyl chloride
2-Fluoro-pyridine-3-sulfonyl chloride can be synthesized through the chlorosulfonation of 2-fluoro-pyridine using concentrated sulfuric acid. The reaction typically occurs at elevated temperatures, and the process requires careful temperature control to prevent side reactions. The yield is generally around 70-80%, and the product can be purified by recrystallization from appropriate solvents.

About

English Name 2-Fluoro-pyridine-3-sulfonyl chloride
Molecular Formula C5H3ClFNO2S
Molecular Weight 195.60199999999998 g/mol
SMILES C1=CC(=C(N=C1)F)S(=O)(=O)Cl
InChIKey MSOAVTSXBMHOEM-UHFFFAOYSA-N
Last Updated: 2026-01-13 15:28

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