How is (2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid (CAS: 850033-39-5) typically synthesized?

(2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid (CAS: 850033-39-5) is commonly synthesized through a multistep process involving the protection of the phenolic hydroxyl group, followed by the introduction of the trifluoromethoxy group, and finally the generation of the boronic acid functionality. This synthesis typically requires catalysts like palladium(II) acetate and ligands such as Xantphos, with high selectivity and yields.