Compound Q&A
How is Folic Acid-d4 (CAS: 171772-72-3) typically synthesized?
Answer
Folic Acid-d4 (CAS: 171777-72-3) is synthesized through the methylation of folic acid with dimethyl sulfate in the presence of a catalyst such as sodium hydroxide. The reaction yields a 95% pure product with high selectivity. The process typically involves dissolving folic acid in a solvent, adding dimethyl sulfate, and then neutralizing with a base to obtain the diastereomerically labeled compound.
About
CAS No
171777-72-3
English Name
Folic Acid-d4
Molecular Formula
C19H19N7O6
Molecular Weight
445.4284071120002 g/mol
SMILES
C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
InChIKey
OVBPIULPVIDEAO-ALIZGMTFSA-N
Last Updated: 2025-12-29 01:16
