Compound Q&A

How is ciprofloxacin-d8 hydrochloride (CAS: 1216659-54-9) typically synthesized?

Answer

Ciprofloxacin-d8, Hydrochloride
Ciprofloxacin-d8 hydrochloride is typically synthesized by alkylation of the amine group of ciprofloxacin with deuterated alkyl halide, followed by addition of hydrochloric acid. The reaction is catalyzed by a phase-transfer catalyst, and the product is obtained with good yield and selectivity.

About

English Name Ciprofloxacin-d8, Hydrochloride
Molecular Formula C17H11D8ClFN3O3
Molecular Weight 375.86 g/mol
SMILES C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.Cl
InChIKey DIOIOSKKIYDRIQ-JCYLEXHWSA-N
Last Updated: 2025-11-07 19:01

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