Compound Q&A

How is Ethyl 2,4-dihydroxy-6-methylnicotinate (CAS: 10350-10-4) typically synthesized?

Answer

Ethyl 2,4-dihydroxy-6-methylnicotinate
Ethyl 2,4-dihydroxy-6-methylnicotinate is typically synthesized through the condensation of 2,4-dihydroxybenzoic acid with ethylamine, followed by a methyl esterification step. This reaction is usually catalyzed by a strong acid such as sulfuric acid, and the yield is generally around 85-90%. The selectivity and purity of the product can be further improved through recrystallization techniques.

About

CAS No 10350-10-4
English Name Ethyl 2,4-dihydroxy-6-methylnicotinate
Molecular Formula C9H11NO4
Molecular Weight 197.19 g/mol
SMILES CCOC(=O)C1=C(C=C(NC1=O)C)O
InChIKey CMCZAWPDHHYFPU-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33

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