(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE(CAS: 119193-19-0)

3-[(3R,4R)-3,4-Dimethyl-4-piperidinyl]phenol is a white crystalline solid with a molecular weight of approximately 268.37 g/mol. It has low water solubility and is soluble in organic solvents such as ethanol and acetone. This compound exhibits moderate reactivity, particularly towards acidic or basic conditions, and shows stability under normal storage conditions.

3-[(3R,4R)-3,4-Dimethyl-4-piperidinyl]phenol is typically synthesized through the condensation of 4-(3,4-dimethylpiperidin-1-yl)benzaldehyde with phenol in the presence of a base such as sodium hydroxide. The reaction involves the formation of a condensation product followed by a reduction step to convert the aldehyde to a phenol.

3-[(3R,4R)-3,4-Dimethyl-4-piperidinyl]phenol is primarily used in the pharmaceutical industry for its biological activity, particularly as a precursor in the synthesis of bioactive compounds. It is also utilized in the production of certain polymers and as a stabilizer in chemical sensors and semiconductors.

When handling 3-[(3R,4R)-3,4-Dimethyl-4-piperidinyl]phenol, appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat should be worn. The compound should be handled in a well-ventilated area or under a fume hood. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. An SDS (Safety Data Sheet) should be consulted for detailed handling and storage instructions.