(1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid

Basic Information

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CAS Number

220497-66-5

Molecular Formula

C21H21NO4

Molecular Weight

351.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

166-168 ºC

Boiling Point

485.2°C (rough estimate)

Solubility

Insuluble (7.0E-3 g/L) (25 ºC),

Refractive Index

1.5614 (estimate)

SMILES

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C1CC(CC1C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C21H21NO4/c23-20(24)13-9-10-14(11-13)22-21(25)26-12-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,13-14,19H,9-12H2,(H,22,25)(H,23,24)/t13-,14+/m0/s1

InChIKey

BHDMUBZVWRSQOT-UONOGXRCSA-N

LogP

3.778400000000002

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

514

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

220497-66-5
(+)-(1S,3R)-N-Fmoc-3-aminocyclopentane-1-carboxylic acid
Fmoc-D-cis-NH(3)cPen-OH
(1R,3S)-N-FMOC-1-Aminocyclopentane-3-carboxylic acid
A878774
Cyclopentanecarboxylicacid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (1S,3R)-
(+)-(1S,3R)-N-Fmoc-3-aminocyclopentanecarboxylic acid, AldrichCPR
(+)-(1S,3R)-N-Fmoc-3-aminocyclopentane carboxylic acid
(1S,3R)-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]cyclopentanecarboxylic acid
AC-7964
(1S,3R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentane-1-carboxylic acid
(+)-(1S,3R)-N-FMOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID
AKOS015948711
DS-5250
SCHEMBL7200022
(1S,3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentane-1-carboxylic acid
(1S,3R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylic acid
(1S,3R)-N-Fmoc-3-aminocyclopentanecarboxylic acid
MFCD01311757
(1S,3R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylicacid
CS-W006821
DTXSID80426502
(1S,3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)cyclopentane-1-carboxylic acid
(1S,3R)-Fmoc-3-aminocyclopentane-1 carboxylic acid
EN300-657455
(-)-(1S,3R)-N-Fmoc-b-homocycloleucine
AK111538
PubChem24004
(1S,3R)-(+)-N-Fmoc-3-aminocyclopentanecarboxylic acid

MDL Number

MFCD01311757

FAQ

What regulatory guidelines apply to (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5)?

The compound (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5) falls under the scope of the REACH regulations in the EU and may require registration if the tonnage threshold is exceeded. In the United States, it is regulated under the Toxic Substances Control Act (TSCA) by the EPA. Additionally, GHS classification is important for labeling and safety data sheets (SDS).

Are there alternatives to (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5) in synthesis?

In the synthesis of (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5), alternative reagents such as other amino acid derivatives or fluorenylmethoxycarbonyl (Fmoc) protected reagents can be used. These alternatives may offer different reactivity profiles and are often chosen based on the specific synthesis requirements.

What is the market or research trend for (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5)?

The market and research trend for (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5) is primarily focused on its use as a building block for peptide and drug synthesis. Recent trends indicate an increasing demand in the pharmaceutical industry for synthetic intermediates with specific functionalities, supporting ongoing research and development in this area.

How should waste containing (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5) be handled?

Waste containing (1S,3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclopentanecarboxylic acid (CAS: 220497-66-5) should be collected in appropriate containers and handled according to local waste disposal regulations. For hazardous waste, incineration or professional waste disposal services should be used, ensuring compliance with environmental protection laws and safety guidelines. Storage and handling should be conducted with proper personal protective equipment (PPE) and in a well-ventilated area.