N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine(CAS: 2083627-02-3)

N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine has a crystalline form and a molecular weight of approximately 415.46 g/mol. It is slightly soluble in water and ethanol. The compound is reactive, showing good stability in neutral and basic conditions, but less so in acidic environments. It has a melting point around 220-225°C and a boiling point of about 450°C.

N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine is synthesized through a multi-step process involving the coupling of 2-furylmethylamine with 8-(4-hydroxyphenyl)-1,2,4-triazolo[4,3-c]pyrimidin-5(4H)-one. The synthesis involves the use of a catalytic amount of a base, such as sodium hydride, and a solvent like dimethylformamide (DMF). The final product is obtained with a yield of approximately 75%.

N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine is primarily used in the pharmaceutical industry for its potential as an antitumor and antiviral agent. It is also utilized in the polymer industry for its applications in the development of functional polymers and in the semiconductor industry for its role in the production of electronic materials.

When handling N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine, it is important to use appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be used in a well-ventilated area or a fume hood. Spills should be managed carefully, and the area should be thoroughly cleaned. In case of exposure, seek medical attention immediately. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.