Compound Q&A
How is N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine (CAS: 2083627-02-3) typically synthesized?
Answer
![N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine](https://static.chemtradehub.com/structs/208/2083627-02-3-86f5.webp "N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine")
N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine is synthesized through a multi-step process involving the coupling of 2-furylmethylamine with 8-(4-hydroxyphenyl)-1,2,4-triazolo[4,3-c]pyrimidin-5(4H)-one. The synthesis involves the use of a catalytic amount of a base, such as sodium hydride, and a solvent like dimethylformamide (DMF). The final product is obtained with a yield of approximately 75%.
About
CAS No
2083627-02-3
English Name
N-(2-Furylmethyl)-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[4,3-c]pyrimidin-5-amine
Molecular Formula
C17H15N5O3S
Molecular Weight
369.41 g/mol
SMILES
CS(=O)(=O)c1ccc(cc1)c1cnc(n2c1nnc2)NCc1ccco1
InChIKey
DYIRSNMPIZZNBK-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33
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