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3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione(CAS: 871700-24-2)

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
CAS Number

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Basic Information

Molecular Formula
C18H15FIN3O4
Molecular Weight
483.24 g/mol

Physical Properties

Boiling Point
518.2±60.0°C at 760 mmHg

Chemical Identifiers

SMILES
O=C1N(C2=CC=C(I)C=C2F)C3=C(C(O)=C(C)C(N3C)=O)C(N1C4CC4)=O
InChIKey
MHHFXMZMCYWCJQ-UHFFFAOYSA-N

Database References

MDL Number
MFCD18207185

FAQ

This compound is a crystalline solid with a high molecular weight and moderate solubility in polar solvents. It exhibits good thermal stability and low reactivity under normal conditions. The compound is not flammable but can undergo substitution reactions under certain conditions.
The compound is synthesized through a multi-step process involving aryl iodination, cyclopropylation, and pyrimidine ring formation. Commonly used catalysts include palladium complexes and base conditions such as sodium hydride. The reaction is selective and yields up to 80% purity.
This compound is primarily used in the pharmaceutical industry for its potential in developing new drugs. It is also explored for applications in polymer science and electronics, particularly in sensor development and semiconductor manufacturing.
Handle this compound in a well-ventilated area or fume hood to avoid inhalation. Wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for more detailed safety information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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