(1R,3S)-1,3-Cyclopentanedicarboxylic acid(CAS: 4056-78-4)

(1R,3S)-1,3-Cyclopentanedicarboxylic acid is a crystalline solid with a molecular weight of approximately 146.17 g/mol. It has a solubility of about 2.5 g/L in water. This compound exhibits moderate reactivity, particularly in esterification and anhydride formation. It's stable under normal conditions but should be stored in a desiccator to prevent moisture absorption.

(1R,3S)-1,3-Cyclopentanedicarboxylic acid can be synthesized through the cyclization of 1,3-cyclopentanedione. This is often achieved using a base like sodium hydroxide in a suitable solvent such as water. The reaction typically yields a high selectivity for the (1R,3S) configuration and a good overall yield, around 70-80%.

(1R,3S)-1,3-Cyclopentanedicarboxylic acid finds applications in various industries, including pharmaceuticals for the production of certain polymers and as a chemical intermediate. It's also used in the manufacturing of sensors and semiconductors due to its unique structural features.

When handling (1R,3S)-1,3-Cyclopentanedicarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store it in a cool, dry place away from moisture and flammable materials. In case of a spill, use appropriate absorbent materials and consult a Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for disposal instructions. Always ensure good ventilation in the work area.