6-Methoxy-2,4(1H,3H)-pyrimidinedione

Basic Information

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CAS Number

29458-38-6

Molecular Formula

C5H6N2O3

Molecular Weight

142.11 g/mol

Basic Physical Properties

SMILES

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COC1=CC(=O)NC(=O)N1

InChI

InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)

InChIKey

SWNDNOHEVRPIDI-UHFFFAOYSA-N

LogP

-0.9282000000000001

Topological Polar Surface Area

74.95 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

209

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

CHEMBL5172278
6-Methoxypyrimidine-2,4-diol
6-Methoxyuracil
2,4-Dihydroxy-6-methoxypyrimidine
DS-2879
SWNDNOHEVRPIDI-UHFFFAOYSA-N
29458-38-6
2,4(1H,3H)-Pyrimidinedione, 6-methoxy-
6-methoxy-1,2,3,4-tetrahydropyrimidine-2,4-dione
19868-01-0
6-methoxy-1H-pyrimidine-2, 4-dione
A876456
AKOS006344243
FT-0638855
J-507225
6-methoxy-1H-pyrimidine-2,4-dione
SB57490
AKOS005423780
MFCD00475644
AC-17060
DTXSID00355906
SCHEMBL3109540
6-Methoxypyrimidine-2 pound not4(1H pound not3H)-dione
CS-0150229
6-methoxypyrimidine-2,4(1H,3H)-dione
IGX
6-Methoxypyrimidine-2,4(1H,3H)-dione
2,4(1H,3H)-Pyrimidinedione,6-methoxy-
2,4-dihydroxy-6-methoxypyrimidine
2,4,6-TRIMETHYPYRIDINE-3,5-DIACETONITRILE
6-Methoxy-1,2,3,4-tetrahydropyrimidin-2,4-dion

MDL Number

MFCD00475644

FAQ

What are the physical and chemical properties of 6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6)?

6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6) is a crystalline solid with a molecular weight of 186.15 g/mol. It is slightly soluble in water and organic solvents. Chemically, it is reactive, particularly towards nucleophiles and bases. This compound is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight and moisture.

How is 6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6) typically synthesized?

6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6) is typically synthesized via the condensation of 2-amino-4-methoxypyrimidine with acetic anhydride. The reaction is catalyzed by an acid and proceeds with high selectivity and good yield. Post-synthesis, the compound is purified by recrystallization from hot water.

What industries use 6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6)?

6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6) is primarily used in the pharmaceutical and polymer industries. It is a key intermediate in the synthesis of various drugs and also serves as a monomer for the production of certain polymers. Additionally, it has applications in sensor technology and semiconductor fabrication.

What precautions should be taken when handling 6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6)?

When handling 6-Methoxy-2,4(1H,3H)-pyrimidinedione (CAS: 29458-38-6), always wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using absorbent materials and disposed of according to local regulations. Refer to the safety data sheet (SDS) for detailed emergency procedures.