4-(Aminomethyl)-2-methoxyphenol(CAS: 1196-92-5)

4-(Aminomethyl)-2-methoxyphenol (CAS: 1196-92-5) is a white to off-white crystalline solid. Its molecular weight is approximately 184.24 g/mol. This compound is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. It is known for its basicity due to the aminomethyl group and can react with acidic compounds to form salts. It is stable under normal storage conditions but should be kept away from strong acids and oxidizers.

4-(Aminomethyl)-2-methoxyphenol (CAS: 1196-92-5) is typically synthesized via the reaction of 2-methoxyacetophenone with ammonia or an ammonia solution in the presence of a suitable catalyst. The method involves the nucleophilic addition of ammonia to the carbonyl group of 2-methoxyacetophenone, followed by reduction of the resulting amide to the aminomethyl group. The yield is usually around 70-80% depending on the reaction conditions.

4-(Aminomethyl)-2-methoxyphenol (CAS: 1196-92-5) finds applications in various industries including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It is also used in the production of dyes and pigments, as a stabilizer in polymer formulations, and in the development of chemical sensors for detecting specific analytes due to its functional groups.

When handling 4-(Aminomethyl)-2-methoxyphenol (CAS: 1196-92-5), it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be cleaned up with care using suitable absorbents, and disposal should follow local regulations. A Material Safety Data Sheet (MSDS) should always be consulted for detailed safety information.