2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride (1:1)(CAS: 635698-30-5)

2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride (CAS: 635698-30-5) crystallizes in a solid form with a molecular weight of approximately 256.02 g/mol. It has a pKa of about 2.5 and is slightly soluble in water, with a solubility of around 0.01 g/100 mL at 25°C. Chemically, it is reactive towards bases and electrophiles. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight and oxidizing agents.

2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride (CAS: 635698-30-5) is typically synthesized through a multi-step process involving the reaction of a pyrimidine derivative with dichloromethane. The synthesis involves the use of Lewis acids as catalysts, such as aluminum chloride, to enhance the reactivity. The yield is generally around 70-80%, and the purity can be improved through recrystallization.

2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride (CAS: 635698-30-5) is widely used in the pharmaceutical industry for its biological activities. It has potential applications in the development of new drugs due to its unique structure. Additionally, it is utilized in the sensor industry for its electronic properties and in the semiconductor industry for its use in the fabrication of organic electronic devices.

When handling 2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride (CAS: 635698-30-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Handle it in a well-ventilated area or fume hood. In case of a spill, neutralize the spill with an appropriate neutralizing agent and follow the specific safety data sheet (SDS) for disposal. Proper storage in a cool, dry place is recommended to avoid degradation under normal conditions.