3-[(1R)-1-Aminoethyl]benzonitrile hydrochloride (1:1)(CAS: 1286693-23-9)

3-[(1R)-1-Aminoethyl]benzonitrile hydrochloride is a white crystalline solid with a molecular weight of approximately 242.64 g/mol. It has a low water solubility and is moderately soluble in organic solvents like methanol and ethanol. This compound is known for its amine group reactivity, which can undergo nucleophilic substitution reactions.

3-[(1R)-1-Aminoethyl]benzonitrile hydrochloride is typically synthesized via a multistep process starting from 3-bromobenzonitrile and (1R)-1-aminoethyl bromide. The reaction involves nucleophilic substitution followed by hydrolysis to form the hydrochloride salt. Commonly used solvents include dichloromethane and ethyl acetate.

This compound is primarily used in the pharmaceutical industry for its amine functional group, which can be useful in drug synthesis. It also finds applications in polymer chemistry as a monomer and in sensor technology due to its reactivity and solubility properties.

Proper personal protective equipment (PPE) should be worn when handling this compound, including gloves and safety goggles. It should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using absorbent materials and suitable waste disposal procedures. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.