5-Bromo-2-chlorobenzoyl chloride(CAS: 21900-52-7)

5-Bromo-2-chlorobenzoyl chloride (CAS: 21900-52-7) is a crystalline solid with a molecular weight of approximately 249.02 g/mol. It has a low solubility in water but is soluble in common organic solvents like dichloromethane, acetone, and ethanol. This compound is reactive, particularly towards nucleophiles, making it useful in various chemical transformations. It is stable under normal conditions but should be stored away from moisture to prevent hydrolysis.

5-Bromo-2-chlorobenzoyl chloride is typically synthesized via a multi-step process involving the bromination and chlorination of benzene, followed by acylation. This process often requires the use of a phase transfer catalyst and generates high yields. The exact method can vary, but common solvents like dichloromethane are used, and the product is isolated by recrystallization.

5-Bromo-2-chlorobenzoyl chloride (CAS: 21900-52-7) finds application in the pharmaceutical, polymer, and chemical synthesis industries. It is used as an intermediate in the synthesis of drugs, polymers, and other organic compounds. Its reactivity makes it valuable for producing functionalized organic molecules with specific properties.

When handling 5-Bromo-2-chlorobenzoyl chloride (CAS: 21900-52-7), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions.