6-Fluoroquinazoline-2,4-diol(CAS: 88145-90-8)

6-Fluoroquinazoline-2,4-diol is a solid with a melting point of 214-216°C. It has a molecular weight of 230.07 g/mol and is slightly soluble in water. It is reactive towards nucleophiles and can undergo various chemical transformations. The compound is stable under normal conditions but should be stored in a cool, dry place away from heat sources and oxidizing agents.

6-Fluoroquinazoline-2,4-diol is typically synthesized via a multi-step reaction involving the conversion of a starting amine to an amide, followed by the introduction of a fluoro group, and finally the reduction of an intermediate aldehyde to obtain the diol. Catalysts like palladium are often used to enhance the selectivity and yield of the reactions.

6-Fluoroquinazoline-2,4-diol is primarily used in the pharmaceutical industry for the development of drug candidates. It may also find applications in the polymer industry for creating functional materials, and in the sensor industry for developing chemical sensors due to its unique chemical properties.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 6-Fluoroquinazoline-2,4-diol. It should be stored in a cool, dry place, away from heat and oxidizing agents. Fume hoods should be used during handling to minimize inhalation risk. In case of a spill, neutralize the spill with an appropriate chemical and clean up with care, following the Safety Data Sheet (SDS) guidelines for this compound.