(3-Fluoro-4-formylphenyl)boronic acid(CAS: 248270-25-9)

(3-Fluoro-4-formylphenyl)boronic acid (CAS: 248270-25-9) is a white crystalline powder. It has a molecular weight of approximately 245.13 g/mol. The compound is sparingly soluble in water but soluble in organic solvents like ethanol and acetonitrile. Chemically, it is known for its reactivity towards nucleophiles and its ability to form stable complexes with transition metals. It is used as a boron source in various synthetic reactions.

(3-Fluoro-4-formylphenyl)boronic acid (CAS: 248270-25-9) is typically synthesized via the coupling of 3-fluoro-4-formylphenol with boron tribromide in an organic solvent. The reaction selectively forms the boronic acid ester with high yield. Commonly, this process is carried out under mild conditions to ensure high selectivity and purity of the product.

(3-Fluoro-4-formylphenyl)boronic acid (CAS: 248270-25-9) is utilized in the pharmaceutical and materials science industries. In pharmaceuticals, it serves as a key intermediate in the synthesis of various drug compounds. In materials science, it is used in the development of advanced polymers and sensors. Its boronic acid functionality makes it particularly useful in organic synthesis and catalysis.

When handling (3-Fluoro-4-formylphenyl)boronic acid (CAS: 248270-25-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures. Storage should be in a cool, dry place, away from heat and sources of ignition.