6-(3-Aminophenyl)picolinic acid(CAS: 1261925-21-6)

6-(3-Aminophenyl)picolinic acid (CAS: 1261925-21-6) is a crystalline solid with a molecular weight of approximately 231.23 g/mol. It is slightly soluble in water and organic solvents. Chemically, it is moderately reactive, particularly with nucleophiles due to the amine group. It exhibits good solubility in polar solvents such as methanol and ethanol. This compound is stable under normal storage conditions but may degrade under acidic or basic conditions.

6-(3-Aminophenyl)picolinic acid can be synthesized through a multi-step process. One common approach involves the reaction of 3-aminophenylamine with picolinoyl chloride in the presence of a base such as triethylamine. This reaction typically yields a racemic mixture. Further purification and separation techniques, such as recrystallization or chromatography, may be required to obtain the desired enantiomeric form. The yield is generally around 70-80%.

6-(3-Aminophenyl)picolinic acid (CAS: 1261925-21-6) is primarily used in pharmaceuticals for its potential as an antimicrobial agent and for its role in the development of new drugs. It also finds application in the chemical industry for the synthesis of other compounds and in research for its biological activities. Additionally, it may be used in some sensor technologies and materials science for its reactive functional groups.

When handling 6-(3-Aminophenyl)picolinic acid (CAS: 1261925-21-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to the compound. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.