Compound Q&A
How is 6-(3-Aminophenyl)picolinic acid (CAS: 1261925-21-6) typically synthesized?
Answer
6-(3-Aminophenyl)picolinic acid can be synthesized through a multi-step process. One common approach involves the reaction of 3-aminophenylamine with picolinoyl chloride in the presence of a base such as triethylamine. This reaction typically yields a racemic mixture. Further purification and separation techniques, such as recrystallization or chromatography, may be required to obtain the desired enantiomeric form. The yield is generally around 70-80%.
About
CAS No
1261925-21-6
English Name
6-(3-Aminophenyl)picolinic acid
Molecular Formula
C12H10N2O2
Molecular Weight
214.22 g/mol
SMILES
C1=CC(=CC(=C1)N)C2=NC(=CC=C2)C(=O)O
InChIKey
APPZUWSRWDJQDL-UHFFFAOYSA-N
Last Updated: 2026-01-13 06:10
