1-(4-Fluorobenzyl)piperazine

Basic Information

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CAS Number

70931-28-1

Molecular Formula

C11H15FN2

Molecular Weight

194.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

64-65 ºC

Boiling Point

278 ºC

Density

1.103

Flash Point

122 ºC

Refractive Index

1.5255-1.5275

Vapor Pressure

0.0±0.6 mmHg at 25°C

SMILES

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C1CN(CCN1)CC2=CC=C(C=C2)F

InChI

InChI=1S/C11H15FN2/c12-11-3-1-10(2-4-11)9-14-7-5-13-6-8-14/h1-4,13H,5-9H2

InChIKey

OOSZCNKVJAVHJI-UHFFFAOYSA-N

LogP

1.2309

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

161

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1-(4-Fluorobenzyl)piperazine
S99A94YLM2
AK-968/13146342
EN300-110643
DTXSID90355314
1-(4-fluorobenzyl)-piperazine
SCHEMBL211040
AKOS000125740
Para-fluoro bzp
70931-28-1
FT-0605710
NS00017537
4-(4-fluorobenzyl)piperazine
1-(4-fluorobenzyl) piperazine
MFCD01075234
4-fluorobenzyl-piperazine
F14907
1-[(4-fluorophenyl)methyl]piperazine
1-(p-fluorobenzyl)piperazine
N-(p-fluorobenzyl)piperazine
OSM-S-446
1-((4-Fluorophenyl)methyl)piperazine
BP-13343
1-(Para-fluorobenzyl)piperazine
FS-1578
p-Fluoro bzp
4-Fluoro bzp
4-fluorobenzylpiperazine
1-(4-Fluoro-benzyl)-piperazine
SODIUMDIHYDROGENPHOSPHATEDIHYDRATE
BB 0249426

MDL Number

MFCD01075234

Customs Code

2933599090

FAQ

What regulatory guidelines apply to 1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1)?

1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and is classified as a skin and eye irritant. In the European Union, it falls under the REACH regulation, requiring suppliers to provide safety data sheets (SDS) and register with ECHA. FDA and EPA have no specific regulations for this compound. It is advisable to consult local regulations and guidelines for handling and storage.

Are there alternatives to 1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1) in synthesis?

There are alternative reagents and starting materials that can be used in the synthesis of 1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1), such as 4-chlorobenzyl piperazine or 4-methylbenzyl piperazine. These alternatives may offer similar functionalities but with different reactivity profiles, allowing for the optimization of synthetic routes based on specific requirements and conditions.

What is the market or research trend for 1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1)?

The market for 1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1) is currently growing due to its potential applications in pharmaceutical research. Recent trends indicate increased interest in its use as a modulator of serotonin receptors. The research community is exploring its role in treating conditions such as depression and anxiety. Additionally, there is ongoing development of new analogs to improve efficacy and reduce side effects.

How should waste containing 1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1) be handled?

Waste containing 1-(4-Fluorobenzyl)piperazine (CAS: 70931-28-1) should be collected in appropriate containers and stored away from heat and ignition sources. It is recommended to neutralize the waste with a suitable base or acid, followed by incineration or professional waste disposal. Environmental protection precautions include proper labeling and adherence to local waste management regulations to prevent contamination of soil and water sources.