tert-butyl 4-hydroxy-3-MethoxybenzylcarbaMate(CAS: 130972-89-3)

Tert-butyl 4-hydroxy-3-MethoxybenzylcarbaMate (CAS: 130972-89-3) is a white crystalline solid with a molecular weight of approximately 285.35 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. It is known for its high reactivity towards nucleophiles and bases due to its phenolic and methoxy groups.

Tert-butyl 4-hydroxy-3-MethoxybenzylcarbaMate is commonly synthesized through a multi-step process involving the protection of a hydroxyl group followed by a benzyl substitution reaction. The synthesis typically uses tert-butyldimethylsilyl chloride as a protecting agent and catalytic amounts of a Lewis acid such as BF3•OEt2 to facilitate the benzylation step. The yield and selectivity can be optimized through careful choice of reaction conditions.

Tert-butyl 4-hydroxy-3-MethoxybenzylcarbaMate is used in various industries, particularly in pharmaceuticals for the synthesis of active pharmaceutical ingredients (APIs) and as a precursor in polymer chemistry for the development of functional polymers. It also has applications in the production of sensors and semiconductors due to its unique chemical properties.

When handling tert-butyl 4-hydroxy-3-MethoxybenzylcarbaMate (CAS: 130972-89-3), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to the compound. Spills should be cleaned up immediately using appropriate neutralizing agents and rinsing with copious amounts of water. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.