2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (1:1)

Basic Information

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CAS Number

456-00-8

Molecular Formula

C8H9ClFNO

Molecular Weight

189.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

234-240°C

SMILES

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C1=CC(=CC=C1C(=O)CN)F.Cl

InChI

InChI=1S/C8H8FNO.ClH/c9-7-3-1-6(2-4-7)8(11)5-10;/h1-4H,5,10H2;1H

InChIKey

KQROOJFZQSQJMM-UHFFFAOYSA-N

LogP

1.3889

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

141

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-amino-1-(4-fluorophenyl)-1-ethanone hydrochloride
A826857
AM20060996
SCHEMBL156632
2-(4-fluoro-phenyl)-2-oxo-ethyl-ammonium chloride
CS-W020378
2-Amino-4'-Fluoro Acetophenone HCl
2-Amino-4'-fluoroacetophenone, HCl
2-amino-4'-fluoracetophenone hydrochloride
2-Amino-4 inverted exclamation mark -fluoroacetophenone Hydrochloride
KQROOJFZQSQJMM-UHFFFAOYSA-N
2-Amino-4-fluoroacetophenone hcl
2-azanyl-1-(4-fluorophenyl)ethanone hydrochloride
2-amino-1-(4-fluoro-phenyl)-ethanone hydrochloride
2-amino-1-(4-fluorophenyl)ethanone;hydrochloride
2-amino-1-(4-fluorophenyl)ethan-1-one hydrochloride
aminomethyl-(4-fluorophenyl)ketone hydrochloride
J-507727
MFCD00193059
2-amino-4'-fluoroacetophenone hydrochloride
A26931
2-AMINO-4'-FLUOROACETOPHENONE.HCL
EN300-117068
2-Amino-1-(4-fluorophenyl)ethanone hydrochloride
2-amino-1-(4-fluorophenyl)ethanonehydrochloride
Ethanone, 2-amino-1-(4-fluorophenyl)-, hydrochloride
2-amino-4'-fluoroacetophenone hydrochloride, AldrichCPR
SY018446
AKOS005070627
DTXSID00535009
CL8844

MDL Number

MFCD00193059

Customs Code

2922399090

FAQ

What regulatory guidelines apply to 2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (CAS: 456-00-8)?

2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (CAS: 456-00-8) is regulated under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), which includes classification as a skin irritant. In the European Union, it is subject to the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation. FDA and EPA regulations also apply for its import, use, and disposal in the United States. Proper safety data sheets (SDSs) should be maintained and reviewed regularly.

Are there alternatives to 2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (CAS: 456-00-8) in synthesis?

There are alternative reagents that can be used in the synthesis of similar compounds. For instance, 2-Amino-1-(phenyl)ethanone or other fluorinated analogs like 2-Amino-1-(3-fluorophenyl)ethanone can serve as alternatives. These alternatives may offer similar functionalities but with different reactivity profiles, which can be advantageous depending on the specific application or desired product.

What is the market or research trend for 2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (CAS: 456-00-8)?

The market for 2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (CAS: 456-00-8) is growing due to its use in pharmaceuticals and agrochemicals. Research trends focus on its application in drug discovery and development, particularly as intermediates for synthesizing active pharmaceutical ingredients. Additionally, there is increasing interest in exploring its use in green chemistry processes and sustainable product development.

How should waste containing 2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (CAS: 456-00-8) be handled?

Waste containing 2-Amino-1-(4-fluorophenyl)ethanone hydrochloride (CAS: 456-00-8) should be handled in accordance with local regulations and guidelines. Proper waste collection should be done, ensuring that it is safely stored in leak-proof containers. For disposal, professionals with appropriate credentials should be consulted. Incineration is a common method for disposal, followed by environmental monitoring to ensure compliance with regulatory standards and safety precautions are taken to prevent environmental contamination.