4-(Dihydroxyboryl)-2-fluorobenzoic acid(CAS: 120153-08-4)

4-(Dihydroxyboryl)-2-fluorobenzoic acid (CAS: 120153-08-4) is a white crystalline solid with a molecular weight of approximately 259.07 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it exhibits acid properties and can undergo typical reactions such as esterification and nucleophilic substitution. It is stable under normal conditions but reacts with strong bases to form the corresponding sodium salt.

4-(Dihydroxyboryl)-2-fluorobenzoic acid can be synthesized by the reaction of 2-fluorobenzoic acid with dihydroxyborane in the presence of a suitable catalyst, typically a Lewis acid like boron trifluoride etherate. The reaction provides high yield and good selectivity, with the final product isolated by filtration and recrystallization.

4-(Dihydroxyboryl)-2-fluorobenzoic acid (CAS: 120153-08-4) is primarily used in pharmaceuticals and research chemistry due to its structural complexity and reactivity. It can also be used in polymer synthesis and as a sensor component, although its specific applications in these areas are limited.

When handling 4-(Dihydroxyboryl)-2-fluorobenzoic acid (CAS: 120153-08-4), wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or fume hood to avoid inhalation or skin contact. Spills should be immediately cleaned up with a suitable absorbent material, followed by thorough washing of the affected area. Refer to the Safety Data Sheet (SDS) for specific guidelines and emergency procedures.