(2,6-Difluoro-3-pyridinyl)boronic acid

Basic Information

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CAS Number

136466-94-9

Molecular Formula

C5H4BF2NO2

Molecular Weight

158.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

314.8°C at 760 mmHg

Density

1.4400

Flash Point

144.2 °C

Refractive Index

1.483

SMILES

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B(C1=C(N=C(C=C1)F)F)(O)O

InChI

InChI=1S/C5H4BF2NO2/c7-4-2-1-3(6(10)11)5(8)9-4/h1-2,10-11H

InChIKey

LCCZTROJRJFXNV-UHFFFAOYSA-N

LogP

-0.9604000000000001

Topological Polar Surface Area

53.35 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

138

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2,6-Difluoro-3-pyridineboronic Acid
(2,6-difluoro-3-pyridinyl)boronic acid
2,6-Difluoropyridine-3-boronic acid
2,6-difluoro-3 pyridylboronic acid
2,6-difluoropyridin-3-ylboronic acid
C5H4BF2NO2
BORONIC ACID, (2,6-DIFLUORO-3-PYRIDINYL)-
136466-94-9
NCGC00249564-01
(2,6-difluoropyridin-3-yl)boronic Acid
2,6-Difluoro-3-pyridineboronicAcid
CS-W000868
AC-33484
AKOS006344171
2,6-difluoro-pyridine-3-boronic acid
FT-0600763
BORONIC ACID, B-(2,6-DIFLUORO-3-PYRIDINYL)-
SCHEMBL426850
Z1201622436
LCCZTROJRJFXNV-UHFFFAOYSA-N
2,6-Difluoro-3-pyridylboronic acid
(2,6-difluoro-3-pyridyl)boronic acid
2,6-Difluoropyridine-3-boronicacid
EN300-7372300
DTXSID90376387
2,6-Difluoropyridine-3-boronic acid, AldrichCPR
2,6-difluoropyridin-3-yl-3-boronic acid
AB15953
GS-6452
D4006
AMY7883

MDL Number

MFCD03788245

Customs Code

2933399090

FAQ

What is (2,6-Difluoro-3-pyridinyl)boronic acid (CAS: 136466-94-9)?

(2,6-Difluoro-3-pyridinyl)boronic acid is an organoboron compound with the chemical formula C6H4BF2C5H2N2O2. It is a white crystalline solid with a pungent odor. This compound is used in various applications including organic synthesis, pharmaceuticals, and materials science.

What are the main uses of (2,6-Difluoro-3-pyridinyl)boronic acid (CAS: 136466-94-9)?

(2,6-Difluoro-3-pyridinyl)boronic acid is primarily used in organic synthesis as a boronic acid for Suzuki coupling reactions. It is also utilized in pharmaceutical research for the synthesis of drug candidates and as a protective group in organic chemistry.

Is (2,6-Difluoro-3-pyridinyl)boronic acid (CAS: 136466-94-9) safe?

(2,6-Difluoro-3-pyridinyl)boronic acid is generally considered safe for handling under normal conditions. However, it should be used in a well-ventilated area and with proper personal protective equipment (PPE) such as gloves and safety glasses. Avoid contact with eyes and skin, and ensure proper disposal of waste materials.

How should (2,6-Difluoro-3-pyridinyl)boronic acid (CAS: 136466-94-9) be stored?

(2,6-Difluoro-3-pyridinyl)boronic acid should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption. Store it at room temperature, and avoid exposure to temperatures above 30°C (86°F).