Compound Q&A

How is 4-(Dihydroxyboryl)-2-fluorobenzoic acid (CAS: 120153-08-4) typically synthesized?

Answer

4-(Dihydroxyboryl)-2-fluorobenzoic acid
4-(Dihydroxyboryl)-2-fluorobenzoic acid can be synthesized by the reaction of 2-fluorobenzoic acid with dihydroxyborane in the presence of a suitable catalyst, typically a Lewis acid like boron trifluoride etherate. The reaction provides high yield and good selectivity, with the final product isolated by filtration and recrystallization.

About

English Name 4-(Dihydroxyboryl)-2-fluorobenzoic acid
Molecular Formula C7H6BFO4
Molecular Weight 183.93099999999998 g/mol
SMILES B(C1=CC(=C(C=C1)C(=O)O)F)(O)O
InChIKey CZDWJVSOQOMYGC-UHFFFAOYSA-N
Last Updated: 2025-10-10 13:51

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