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(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide(CAS: 257933-82-7)

(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide
CAS Number

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Other Suppliers for (2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide

Basic Information

Molecular Formula
C24H23ClFN5O2
Molecular Weight
456.95 g/mol

Physical Properties

Melting Point
198°C(lit.)
Boiling Point
655.5°C at 760 mmHg

Chemical Identifiers

SMILES
CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)C=CCN(C)C
InChIKey
WVUNYSQLFKLYNI-AATRIKPKSA-N

Database References

MDL Number
MFCD09837868

FAQ

This compound is in a crystalline form. It has a molecular weight of approximately 624 g/mol and is slightly soluble in common organic solvents such as methanol and acetonitrile. It shows moderate reactivity with nucleophiles and is stable under neutral conditions but can be sensitive to strong oxidizing agents. It is typically used in synthesis without significant issues due to its chemical stability.
This compound is typically synthesized via a multi-step route involving the condensation of a 3-cyano-7-ethoxy-6-quinolinone derivative with a 4-aminophenylamine containing a 3-chloro-4-fluorophenyl group, followed by a series of alkylation and amidation reactions. The synthesis involves the use of standard reagents and catalysts under mild to moderate conditions, with good selectivity and yield.
This compound is primarily used in the pharmaceutical industry for the development of novel drug candidates due to its specific binding affinity to certain targets. It also finds applications in the polymer industry for the synthesis of advanced materials and in the electronic industry for use in semiconductor and sensor technologies.
When handling this compound, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a dry, well-ventilated area and away from strong oxidizing agents. In the event of a spill, it should be cleaned up carefully following standard laboratory protocols, and the Material Safety Data Sheet (MSDS) should be consulted for detailed emergency procedures.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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