2-Bromo-6-methyl-3-nitropyridine(CAS: 374633-31-5)

2-Bromo-6-methyl-3-nitropyridine is a solid with a crystalline form. Its molecular weight is approximately 235.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. It is moderately reactive, particularly with reducing agents. The compound is stable under normal conditions but should be stored away from moisture and oxidizing agents.

2-Bromo-6-methyl-3-nitropyridine is typically synthesized via a nitration of 6-methyl-3-pyridylamine followed by bromination. Commonly used reagents include nitric acid and sulfuric acid for nitration, and N-bromosuccinimide (NBS) for bromination. The synthesis yields around 75-80%, with high selectivity and good purity.

2-Bromo-6-methyl-3-nitropyridine is used in the pharmaceutical industry as a precursor for certain drug molecules. It also finds applications in the synthesis of organic polymers and as a component in sensors and semiconductors, due to its unique electronic properties.

When handling 2-Bromo-6-methyl-3-nitropyridine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.