2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (1:1)

Basic Information

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CAS Number

86604-74-2

Molecular Formula

C8H11Cl2NO

Molecular Weight

208.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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Cl.COc1ccnc(CCl)c1C

InChI

InChI=1S/C8H10ClNO.ClH/c1-6-7(5-9)10-4-3-8(6)11-2;/h3-4H,5H2,1-2H3;1H

InChIKey

WHAGSNVVBXOIGQ-UHFFFAOYSA-N

LogP

2.5592200000000007

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride
2-Chloromethyl-4-methoxy-3-methylpyridine Hydrochloride
2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (1:1)
Pyridine, 2-(chloromethyl)-4-methoxy-3-methyl-, hydrochloride
2-(chloromethyl)-4-methoxy-3-methylpyridine
hydrochloride (1:1)

MDL Number

MFCD03425333

FAQ

What are the physical and chemical properties of 2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (CAS: 86604-74-2)?

This compound has a crystalline form and a molecular weight of approximately 233.67 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound shows moderate reactivity with nucleophiles and is stable under normal temperature and pressure conditions.

How is 2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (CAS: 86604-74-2) typically synthesized?

This compound is typically synthesized by the reaction of 2-(methylamino)-3-methylpyridine with methyl chloromethyl ether in the presence of a catalytic amount of a base like sodium hydride. The reaction yields a product with high selectivity and good yield.

What industries use 2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (CAS: 86604-74-2)?

This compound is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for modifying polymers. Additionally, it can be used in the sensor industry for selective gas detection.

What precautions should be taken when handling 2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (CAS: 86604-74-2)?

When handling this compound, it is important to use personal protective equipment such as gloves and safety goggles. The compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and the area should be well rinsed. A safety data sheet (SDS) should be consulted for specific handling and disposal information.