[5-(Methoxycarbonyl)-3-pyridinyl]boronic acid(CAS: 871329-53-2)

[5-(Methoxycarbonyl)-3-pyridinyl]boronic acid is a crystalline solid with a molecular weight of approximately 258.26 g/mol. It is sparingly soluble in water and organic solvents. Chemically, it is reactive towards bases and may undergo deprotection or other transformations under certain conditions. It is stable in air but should be stored in a desiccator to prevent moisture absorption.

[5-(Methoxycarbonyl)-3-pyridinyl]boronic acid is commonly synthesized via a multistep process involving the protection of the pyridine ring, followed by the introduction of the methoxycarbonyl group, and finally the formation of the boronic acid moiety. This process often uses reagents such as methoxycarbonyl chloride, boronic acids, and palladium catalysts. The overall yield can vary, but efficient methods can achieve up to 85% yield.

[5-(Methoxycarbonyl)-3-pyridinyl]boronic acid finds applications in pharmaceuticals, where it serves as a building block for drug synthesis, and in polymer science, where it is used as a monomer or crosslinker. It is also used in sensor technology for detecting various analytes and in semiconductor manufacturing for etching and other processes.

PPE such as gloves and goggles should be worn when handling [5-(Methoxycarbonyl)-3-pyridinyl]boronic acid. It should be stored in a fume hood to minimize exposure. In case of a spill, it should be carefully cleaned up using appropriate absorbents. Emergency showers and eye wash stations should be available. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.