Methyl 2,3-dihydrobenzofuran-5-carboxylate(CAS: 588702-80-1)

Methyl 2,3-dihydrobenzofuran-5-carboxylate (CAS: 588702-80-1) is a white crystalline solid with a molecular weight of approximately 217.23 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is less reactive than carboxylic acids but can undergo typical carboxylic acid reactions such as esterification and ester hydrolysis. It exhibits moderate acidity and can form salts with bases.

Methyl 2,3-dihydrobenzofuran-5-carboxylate (CAS: 588702-80-1) can be synthesized via the condensation of methyl 2,3-dihydrobenzofuran-5-carboxylic acid chloride with an amine in the presence of a base. Alternatively, it can be obtained by the reaction of methyl 2,3-dihydrobenzofuran-5-carboxylic acid with an alcohol in the presence of a acid catalyst, yielding an ester. The yield is generally around 70-80%.

Methyl 2,3-dihydrobenzofuran-5-carboxylate (CAS: 588702-80-1) is used in various industries, particularly in the pharmaceutical and chemical sectors. It serves as a key intermediate in the synthesis of pharmaceuticals, where its chemical properties facilitate the creation of more complex molecules. It is also utilized in the production of certain polymers and as a component in sensor technology and semiconductor manufacturing, owing to its functional groups that can participate in various chemical reactions.

When handling Methyl 2,3-dihydrobenzofuran-5-carboxylate (CAS: 588702-80-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to protect against skin and eye contact. Work in a well-ventilated area or fume hood to minimize inhalation exposure. Spills should be cleaned up using appropriate absorbent materials and the area thoroughly rinsed with water. Always refer to the material safety data sheet (MSDS) for detailed safety information and follow all recommended safety procedures.