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Tetrahydrofolic Acid(CAS: 135-16-0)

Tetrahydrofolic Acid
CAS Number

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Basic Information

Molecular Formula
C19H23N7O6
Molecular Weight
445.44 g/mol

Physical Properties

Boiling Point
555.12°C (rough estimate)

Chemical Identifiers

SMILES
C1C(NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
InChIKey
MSTNYGQPCMXVAQ-KIYNQFGBSA-N

Database References

MDL Number
MFCD00135583

FAQ

Tetrahydrofolic Acid (THFA, CAS: 135-16-0) is a crystalline compound with a molecular weight of approximately 136.13 g/mol. It has a solubility of about 0.1 g per 100 mL in water and is slightly soluble in ethanol. THFA is relatively stable but can react with strong oxidizing agents. It is an important intermediate in organic synthesis and biochemical processes.
Tetrahydrofolic Acid (THFA, CAS: 135-16-0) is commonly synthesized via reduction of folic acid using sodium borohydride. This process involves the use of methanol as a solvent, and the reaction yields a high purity product. The reaction is typically carried out in a fume hood to manage any potential inhalation hazards.
Tetrahydrofolic Acid (THFA, CAS: 135-16-0) is widely used in the pharmaceutical industry for the production of folate supplements and medications. It is also used in the food industry as a fortifying agent. Additionally, THFA has applications in the production of certain polymers and in biochemical research.
When handling Tetrahydrofolic Acid (THFA, CAS: 135-16-0), it is important to use personal protective equipment (PPE) such as gloves and goggles. THFA should be stored in a cool, dry place away from direct sunlight. In the event of a spill, immediately clean up the area using appropriate absorbents and dispose of the material according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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