Ethyl 4-[(2-amino-4-chlorophenyl)amino]-1-piperidinecarboxylate(CAS: 53786-45-1)

Ethyl 4-[(2-amino-4-chlorophenyl)amino]-1-piperidinecarboxylate (CAS: 53786-45-1) is a white to off-white crystalline solid with a molecular weight of approximately 333.74 g/mol. It has a solubility of 0.12 g/100 mL in water. This compound is reactive, particularly with bases, and could undergo hydrolysis under basic conditions. It is sparingly soluble in common organic solvents like ethanol and acetone.

Ethyl 4-[(2-amino-4-chlorophenyl)amino]-1-piperidinecarboxylate (CAS: 53786-45-1) is typically synthesized through a multi-step process involving the reaction of 2-amino-4-chloroaniline with 1-aminopiperidine-4-carboxylic acid ethyl ester. The synthesis involves the formation of an intermediate amine compound followed by piperidine substitution to yield the final product. The process requires careful control over temperature and pH to achieve high selectivity and yield.

Ethyl 4-[(2-amino-4-chlorophenyl)amino]-1-piperidinecarboxylate (CAS: 53786-45-1) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the sensor technology and semiconductor industries due to its specific chemical properties. In polymer science, it can be used as a functional monomer or additive.

When handling Ethyl 4-[(2-amino-4-chlorophenyl)amino]-1-piperidinecarboxylate (CAS: 53786-45-1), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle the compound under a fume hood to avoid inhalation. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal. This compound is reactive and can cause skin irritation, so it is important to avoid contact with the skin and eyes.