5-Phenyl-1H-pyrrol-3-yl N-[(4-methylphenyl)sulfonyl]alaninate(CAS: 99740-00-8)

5-Phenyl-1H-pyrrol-3-yl N-[(4-methylphenyl)sulfonyl]alaninate is a crystalline compound with a molecular weight of approximately 333.37 g/mol. It has good solubility in organic solvents such as dichloromethane and poor solubility in water. The compound is chemically stable under normal conditions but may react with strong acids and bases. It is insoluble in aqueous solutions and has limited reactivity in general.

5-Phenyl-1H-pyrrol-3-yl N-[(4-methylphenyl)sulfonyl]alaninate is typically synthesized through a multi-step process involving the reaction of 5-phenyl-1H-pyrrole with 4-methylphenylsulfonyl chloride followed by coupling with alanine. The synthesis usually employs conditions that favor the formation of the desired product, with high selectivity and yield. Commonly used catalysts include triethylamine and HOBt (1-Hydroxybenzotriazole), which enhance the chemical reaction and improve the yield.

5-Phenyl-1H-pyrrol-3-yl N-[(4-methylphenyl)sulfonyl]alaninate is primarily used in the pharmaceutical industry for the development of novel drugs and in the polymer industry for the synthesis of advanced materials. It also finds applications in the development of sensors and as a precursor in semiconductor manufacturing. The compound’s unique chemical structure makes it suitable for various advanced chemical applications requiring high purity and specific functionalities.

When handling 5-Phenyl-1H-pyrrol-3-yl N-[(4-methylphenyl)sulfonyl]alaninate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a fume hood or a well-ventilated area to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Safety data sheets (SDS) should be readily available for reference in case of emergencies. Due to its chemical stability, it is important to follow standard laboratory safety protocols to ensure safe handling and storage.