1,2,3,4-Tetrachloro-5-nitrobenzene(CAS: 879-39-0)

1,2,3,4-Tetrachloro-5-nitrobenzene (CAS: 879-39-0) is a crystalline solid with a molecular weight of approximately 286.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is moderately reactive, particularly towards nucleophilic substitution and reduction reactions. It decomposes upon heating and is sensitive to light.

1,2,3,4-Tetrachloro-5-nitrobenzene (CAS: 879-39-0) is synthesized through the chlorination of 1-nitrobenzene followed by further chlorination. Commonly, this involves the reaction of 1-nitrobenzene with chlorine gas in the presence of a Lewis acid catalyst like aluminum chloride. The final step involves another chlorination to introduce the fourth chlorine atom.

1,2,3,4-Tetrachloro-5-nitrobenzene (CAS: 879-39-0) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring chlorinated and nitro functionalities. It is also utilized in the production of chemical intermediates and for the development of sensors and other specialized applications.

When handling 1,2,3,4-Tetrachloro-5-nitrobenzene (CAS: 879-39-0), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure to vapors. Spills should be handled with care, using absorbent materials, and the area should be thoroughly cleaned. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.