2-Chloro-4-methoxy-1-nitrobenzene(CAS: 28987-59-9)

2-Chloro-4-methoxy-1-nitrobenzene (CAS: 28987-59-9) is a solid at room temperature with a crystalline form. It has a molecular weight of approximately 210.04 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, especially with reducing agents and bases. It can undergo nitro reduction, chlorination, and methoxy elimination reactions under controlled conditions.

2-Chloro-4-methoxy-1-nitrobenzene (CAS: 28987-59-9) is commonly synthesized by the nitration of 2-chloro-4-methoxybenzene. This is typically carried out in the presence of concentrated sulfuric acid as a catalyst. The reaction is performed at low temperature to control the rate of nitration. Selectivity and yield are influenced by the reaction temperature and the concentration of the reactants.

2-Chloro-4-methoxy-1-nitrobenzene (CAS: 28987-59-9) is primarily used in the pharmaceutical industry for the synthesis of various intermediates and active pharmaceutical ingredients. It is also utilized in the production of dyes and pigments due to its aromatic structure. Additionally, it can be employed in the development of sensors and as a precursor in semiconductor manufacturing.

2-Chloro-4-methoxy-1-nitrobenzene (CAS: 28987-59-9) should be handled with caution due to its chemical reactivity. Always wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal procedures.