N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine | CAS No. 183321-74-6

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine

Basic Information

CAS Number

183321-74-6

Molecular Formula

C22H23N3O4

Molecular Weight

393.4 g/mol

AD

Basic Physical Properties

Melting Point

223 - 228 °C

Boiling Point

553.6°C at 760 mmHg

Flash Point

288.6 °C

COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC

InChI

InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)

InChIKey

AAKJLRGGTJKAMG-UHFFFAOYSA-N

LogP

2.7

Complexity

525

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • NS00006169
  • BE164419
  • CCG-220420
  • R1415
  • DB00530
  • Erlotinib(Tarceva)
  • N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
  • UNII-J4T82NDH7E
  • Q418369
  • OSI-744
  • nchembio866-comp3
  • CAS-183321-74-6
  • AB01273955-01
  • CS-0620
  • HMS3745M05
  • BRD-K70401845-003-04-7
  • (6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl)-(3-ethynyl-phenyl)-amine
  • 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline
  • NCGC00164574-03
  • Ro-508231
  • HMS3244M20
  • SY028059
  • [6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE
  • HMS3244M19
  • 183321-74-6 (free base)
  • GTPL4920
  • 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-
  • Z2588038919
  • HMS3295A19
  • HY-50896
  • CHEMBL553

MDL Number

MFCD02089651

FAQ

What is N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6)?

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6) is a synthetic organic compound belonging to the quinazoline class. It contains a quinazolinamine ring with two methoxyethoxy substituents and an ethynylphenyl group. This compound is known for its complex structure and potential applications in medicinal chemistry.

What are the main uses of N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6)?

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6) is primarily used in pharmaceutical research as a potential lead compound for drug development. It may be relevant in the synthesis of compounds targeting specific biological pathways, such as those involved in cancer or neurological disorders.

Is N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6) safe?

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6) is generally considered safe when handled properly in controlled environments. However, as with many organic compounds, it should be treated with care, and appropriate safety measures such as personal protective equipment and ventilation should be followed to minimize exposure risks.

How should N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6) be stored?

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (CAS: 183321-74-6) should be stored in a cool, dry, and light-protected environment. It is typically kept in a sealed container at temperatures below 25°C to maintain stability. Avoid exposure to moisture and air to prevent degradation.

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