1-Nitro-4-(trifluoromethoxy)benzene(CAS: 713-65-5)

1-Nitro-4-(trifluoromethoxy)benzene (CAS: 713-65-5) is a crystalline solid with a molecular weight of approximately 220.05 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. This compound is reactive towards nucleophiles and reducing agents. It is commonly used in the synthesis of pharmaceuticals and electronic materials due to its unique electronic properties.

1-Nitro-4-(trifluoromethoxy)benzene (CAS: 713-65-5) is typically synthesized via a nitration process of 4-(trifluoromethoxy)benzene using a mixture of nitric acid and sulfuric acid. The reaction is carried out under fuming nitric acid conditions to ensure high selectivity and yield. Commonly, the use of a phase transfer catalyst is employed to improve the reaction rate and purity of the product.

1-Nitro-4-(trifluoromethoxy)benzene (CAS: 713-65-5) is used in various industries, particularly in pharmaceuticals and electronics. It serves as a key intermediate in the synthesis of drugs and is also utilized in the production of electronic materials due to its unique chemical and physical properties. Additionally, it is employed in the development of sensors and semiconductor materials.

When handling 1-Nitro-4-(trifluoromethoxy)benzene (CAS: 713-65-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight and sources of ignition. Fume hoods should be used during handling to avoid inhalation of vapors. In case of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal. Always refer to the latest SDS for detailed safety information.