(3,4,5-Trifluorophenyl)boronic acid

Basic Information

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CAS Number

143418-49-9

Molecular Formula

C6H4BF3O2

Molecular Weight

175.9 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

290-295 °C

Boiling Point

263.6 oC at 760 mmHg

Density

1,087g/cm

Flash Point

113.2℃

Solubility

18.43g/l

Refractive Index

1,423-1,425

SMILES

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FC1=C(F)C(F)=CC(B(O)O)=C1

InChI

InChI=1S/C6H4BF3O2/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,11-12H

InChIKey

UHDDEIOYXFXNNJ-UHFFFAOYSA-N

LogP

-0.21629999999999994

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

146

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

(3,4,5-Trifluorophenyl)boronic acid
3,4,5-TRIFLUOROPHENYL BORONIC ACID
BORONIC ACID, B-(3,4,5-TRIFLUOROPHENYL)-
AKOS BRN-0138
3,4,5-TRIFLUOROBENZENEBORONIC ACID
3,4,5-Trifluophenylboronic acid
3,4,5-Trifluorophenylboronic acid (contains varying aMounts of Anhydride)
3,4,5-Trifluorophenylboronic acid
(3,4,5-trifluorophenyl)boranediol
3,4,5-Trifluorphenylboronic acid
Boronic acid, (3,4,5-trifluorophenyl)-
3,4,5-Trifluorophenylboronicacid
PubChem2340
KSC174M0B
Jsp002547
UHDDEIOYXFXNNJ-UHFFFAOYSA-N
3,4,5-Trifluorobenzeneboronic acid

MDL Number

MFCD02093069

Customs Code

2931900090

FAQ

What is (3,4,5-Trifluorophenyl)boronic acid (CAS: 143418-49-9)?

(3,4,5-Trifluorophenyl)boronic acid is a chemical compound with the CAS number 143418-49-9. It has the molecular formula C6H5BrF3O and is characterized by its trifluorophenyl group attached to a boronic acid moiety. This compound is known for its stability and reactivity in organic synthesis, commonly used as a building block in pharmaceutical and industrial applications.

What are the main uses of (3,4,5-Trifluorophenyl)boronic acid (CAS: 143418-49-9)?

(3,4,5-Trifluorophenyl)boronic acid (CAS: 143418-49-9) is widely utilized in the pharmaceutical industry for the synthesis of various drugs, including anti-cancer agents and anti-inflammatory compounds. It also finds applications in organic chemistry research, polymer science, and as a precursor in the development of agrochemicals and materials science products.

Is (3,4,5-Trifluorophenyl)boronic acid (CAS: 143418-49-9) safe?

While (3,4,5-Trifluorophenyl)boronic acid (CAS: 143418-49-9) is generally considered safe when handled properly, it should be treated with caution. It may cause skin and eye irritation, and inhalation or ingestion can be harmful. Protective gloves, goggles, and ventilation are recommended during handling, and it should be stored away from incompatible materials to ensure safety.

How should (3,4,5-Trifluorophenyl)boronic acid (CAS: 143418-49-9) be stored?

(3,4,5-Trifluorophenyl)boronic acid (CAS: 143418-49-9) should be stored in a cool, dry, and well-ventilated area, away from direct light. It is typically kept in a sealed container to prevent moisture absorption and contamination. Proper storage conditions help maintain its stability and prolong shelf life, ensuring it remains effective for its intended uses.