1-Chloro-4-methoxybenzene

Basic Information

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CAS Number

623-12-1

Molecular Formula

C7H7ClO

Molecular Weight

142.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

-18°C

Boiling Point

198°C

Density

1.164 g/mL at 25 °C

Refractive Index

n20/D 1.535(lit.)

SMILES

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COC1=CC=C(C=C1)Cl

InChI

InChI=1S/C7H7ClO/c1-9-7-4-2-6(8)3-5-7/h2-5H,1H3

InChIKey

YRGAYAGBVIXNAQ-UHFFFAOYSA-N

LogP

2.3486000000000002

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

Safety Information

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GHS Hazard Pictograms

H227

Hazard Statement

H227 Combustible liquid
Flammable liquids

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Synonyms & References

English

p-methoxychlorobenzene
1219804-86-0
4-METHOXYCHLOROBENZENE
W-105012
4-Chloroanisole--d4
P-CHLOROANISOLE
0F18BLY08Q
AKOS008948222
4-Chloroanisole, 99%
4-Chlorophenol methyl ether
Anisole, p-chloro-
A833710
FT-0618165
MFCD00000616
AI3-07211
AS-12682
AMY5182
F0001-1669
NSC-4129
SY005701
EINECS 210-772-2
4-chloroanisol
SCHEMBL12015226
UNII-0F18BLY08Q
6H-Cyclohepta[b]quinolin-11-amine, 7,8,9,10-tetrahydro-
NSC4129
NS00035003
NSC 4129
p-anisolyl chloride
4-CHLOROPHENYL METHYL ETHER
p-Chlorophenyl methyl ether

MDL Number

MFCD00000616

Customs Code

29093090

FAQ

What is 1-Chloro-4-methoxybenzene (CAS: 623-12-1)?

1-Chloro-4-methoxybenzene (CAS: 623-12-1) is a chlorinated aromatic compound with the chemical formula C7H8ClO2. It features a benzene ring substituted with a chlorine atom at position 1 and a methoxy group at position 4. This compound is commonly used as an intermediate in organic synthesis and exhibits solubility in organic solvents. Its physical properties include a colorless liquid state at room temperature and a moderately polar character due to the methoxy functional group.

What are the main uses of 1-Chloro-4-methoxybenzene (CAS: 623-12-1)?

1-Chloro-4-methoxybenzene (CAS: 623-12-1) is widely utilized in pharmaceuticals as a building block for drug development, in agrochemicals for herbicide synthesis, and in research for creating derivatives with diverse applications. It also serves as an intermediate in the production of dyes, perfumes, and specialty chemicals. Its reactivity and functional group versatility make it valuable in industrial processes involving aromatic substitution reactions.

Is 1-Chloro-4-methoxybenzene (CAS: 623-12-1) safe?

1-Chloro-4-methoxybenzene (CAS: 623-12-1) requires careful handling due to its potential toxicity. Inhalation or skin contact may cause irritation, and it is classified as a hazardous chemical under safety standards. Precautions include using appropriate personal protective equipment (PPE) and ensuring proper ventilation. Always follow safety data sheet (SDS) guidelines to minimize risks associated with its use.

How should 1-Chloro-4-methoxybenzene (CAS: 623-12-1) be stored?

1-Chloro-4-methoxybenzene (CAS: 623-12-1) should be stored in a sealed, airtight container in a cool (20-25°C), dry, and well-ventilated area. It is sensitive to light, so storage in dark conditions is recommended. Keep away from incompatible substances and maintain low humidity to ensure stability. Use inert material containers and follow recommended storage practices to prevent degradation or hazardous reactions.