Nelarabine(CAS: 121032-29-9)

Nelarabine is a chemotherapy drug primarily used in the treatment of certain types of leukemia. Its chemical name is 2-amino-2-deoxy-1-beta-D-ribofuranosyl-1,3-dihydro-4H-pyrazol-4-one. It is a white to off-white crystalline solid with a molecular weight of 265.26 g/mol and is soluble in water and some organic solvents.

Nelarabine is mainly used in oncology for treating T-cell lymphoblastic leukemia and lymphoma. It functions as a nucleoside analog, inhibiting DNA synthesis in cancer cells. It is also used in research for studying DNA repair mechanisms and as a tool in pharmaceutical development for antiviral and anticancer compounds.

Nelarabine is generally safe when used under medical supervision, but it can cause side effects such as bone marrow suppression and gastrointestinal issues. Proper handling and adherence to safety guidelines are essential. It is classified as a pharmaceutical compound with specific safety standards in place for its use in clinical settings.

Nelarabine should be stored in a cool, dry place away from light. It is typically kept in airtight containers at a temperature between 15°C to 25°C. Proper storage ensures stability and prevents degradation, maintaining its efficacy for pharmaceutical use.