Agomelatine | CAS No. 138112-76-2

Agomelatine

Basic Information

View in Editor

CAS Number

138112-76-2

Molecular Formula

C15H17NO2

Molecular Weight

243.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

108.0 to 112.0 deg-C

Boiling Point

478.8±28.0°C at 760 mmHg

Density

1.109

Flash Point

243.4±24.0 °C

Solubility

DMSO: >50mg/mL

SMILES

View in Editor

CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC

InChI

InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)

InChIKey

YJYPHIXNFHFHND-UHFFFAOYSA-N

LogP

2.527

Topological Polar Surface Area

38.33 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

280

Safety Information

View Safety Information

GHS Hazard Pictograms

H400

Hazard Statement

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Synonyms & References

English

N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide
Agomelatine
AGO 178
NCGC00253646-01
NS00007664
Melitor
AWY
SMR002530056
HMS3884A07
Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-
L000528
Agomelatine (INN)
AGOMELATINE [EMA EPAR]
HY-17038
MLS006011913
SR-01000944938
PDSP1_001784
CS-0740
DTXSID3057642
N-[2-(7-Methoxy-1-naphthalenyl)ethyl]-acetamide
PDSP2_001289
BCP02084
AC-3395
SCHEMBL114476
AB01274769-01
N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide
138112-76-2
Agomelatine, >=98% (HPLC)
BA167079
SW219177-1
Valdoxan (TN)

MDL Number

MFCD00916659

Customs Code

2924199090

FAQ

What is Agomelatine (CAS: 138112-76-2)?

Agomelatine is a novel antidepressant medication with the chemical formula C19H21NO3S. It is a melatonergic agent that modulates serotonin and melatonin receptors, making it effective in treating major depressive disorder. Agomelatine is known for its dual mechanism of action, targeting both serotonin 5-HT2A receptors and melatonin MT1/MT2 receptors.

What are the main uses of Agomelatine (CAS: 138112-76-2)?

Agomelatine is primarily used as an antidepressant in the treatment of major depressive disorder. It is also prescribed for seasonal affective disorder and may be used off-label for other psychiatric conditions. Its unique pharmacological profile makes it a valuable option in managing mood disorders, particularly in patients who do not respond well to traditional antidepressants.

Is Agomelatine (CAS: 138112-76-2) safe?

Agomelatine is generally considered safe when used as directed, but it should be handled with care. It is important to follow prescribed dosages and consult healthcare professionals. Safety guidelines include avoiding use in patients with a history of severe liver disease and monitoring for potential side effects such as drowsiness or gastrointestinal issues.

How should Agomelatine (CAS: 138112-76-2) be stored?

Agomelatine should be stored in a cool, dry place away from direct light. It is typically kept in a sealed container at a temperature between 15°C to 30°C. Proper storage helps maintain its chemical stability and potency. Always check the product label for specific storage instructions and expiration date.