4-[(4-Bromobenzyl)oxy]quinazoline(CAS: 737818-56-3)

4-[(4-Bromobenzyl)oxy]quinazoline (CAS: 737818-56-3) is a crystalline solid with a molecular weight of approximately 354.05 g/mol. It has a melting point of around 210-212°C and is poorly soluble in water but soluble in organic solvents like dichloromethane and methanol. Chemically, it is less reactive towards common acids and bases but can undergo nucleophilic substitution reactions. It is stable under normal laboratory conditions but should be stored in a cool, dry place away from direct sunlight.

4-[(4-Bromobenzyl)oxy]quinazoline (CAS: 737818-56-3) is typically synthesized via a multi-step process involving the reaction of quinazoline with 4-bromobenzyl alcohol. The synthesis involves protecting the amine group, followed by a coupling reaction and deprotection. The overall reaction yields approximately 60-70% of the target compound, and the process is conducted under mild conditions using catalytic amounts of a suitable reagent. Proper workup and purification techniques are necessary to isolate the final product.

4-[(4-Bromobenzyl)oxy]quinazoline (CAS: 737818-56-3) is used in a variety of industries, including pharmaceuticals, where it serves as a potential intermediate in drug synthesis. It also finds applications in the development of sensors and semiconductors due to its unique chemical properties. The compound's ability to participate in specific reactions makes it valuable in the research and development of new materials and pharmaceuticals.

When handling 4-[(4-Bromobenzyl)oxy]quinazoline (CAS: 737818-56-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up promptly using appropriate absorbents, and the area should be well-ventilated. It is crucial to have a Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) readily available in case of any emergencies. Storage should be in a cool, dry place away from direct sunlight and flammable materials.