methyl 3-iodo-1H-indazole-5-carboxylate(CAS: 885271-25-0)

Methyl 3-iodo-1H-indazole-5-carboxylate (CAS: 885271-25-0) is a crystalline solid with a molecular weight of approximately 330.03 g/mol. It has poor water solubility but is soluble in organic solvents like dichloromethane and acetonitrile. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal storage conditions but should be handled with care due to its reactivity.

Methyl 3-iodo-1H-indazole-5-carboxylate (CAS: 885271-25-0) is typically synthesized via a reaction between methyl 3-bromo-1H-indazole-5-carboxylate and sodium iodide in the presence of an appropriate base such as sodium hydride. The reaction yields the desired compound with good selectivity and moderate to high yields, depending on the conditions.

Methyl 3-iodo-1H-indazole-5-carboxylate (CAS: 885271-25-0) is primarily used in the pharmaceutical industry for the synthesis of complex organic compounds. It may also find applications in the polymer industry for developing new materials with specific properties. Additionally, it could be of interest in the sensor technology and semiconductor industries for specialized applications.

When handling methyl 3-iodo-1H-indazole-5-carboxylate (CAS: 885271-25-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood due to its potential volatility and reactivity. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be thoroughly washed. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.