N-(4-Nitrophenyl)acetamide(CAS: 104-04-1)

N-(4-Nitrophenyl)acetamide (CAS: 104-04-1) is a white crystalline solid with a molecular weight of approximately 191.13 g/mol. It has a melting point of 122-124°C and is slightly soluble in water. It is stable under normal conditions but can react with strong bases to form 4-nitrophenol. It is also known to be sensitive to light and heat.

N-(4-Nitrophenyl)acetamide is typically synthesized by the acetylation of 4-nitrophenol using acetic anhydride in the presence of a catalyst such as pyridine. The reaction is carried out at room temperature, and the yield is generally around 85-90%. The product is then purified by recrystallization.

N-(4-Nitrophenyl)acetamide (CAS: 104-04-1) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used in the polymer industry for the production of special resins and adhesives. Additionally, it is used in the development of sensors and semiconductors.

When handling N-(4-Nitrophenyl)acetamide (CAS: 104-04-1), use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place, away from direct sunlight and heat sources. Handle in a fume hood to avoid inhalation. In case of spills, neutralize with an appropriate alkali and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.